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DR. RODNEY OUELLETTE, President and Scientific Director
FRANÇOISE ROY, Executive Director
HAI LeQUANG, Director of Finance & Administration
DR. RODNEY OUELLETTE, PRESIDENT AND SCIENTIFIC DIRECTOR
 
 
As founding Scientific Director, Dr Ouellette has assembled a multi-disciplinary team of dedicated scientists. Under his leadership, ACRI has become a premier research facility in Atlantic Canada, with a growing team of 40 people, and has been awarded more than $28 million in research funding.
 
Dr Ouellette received both his MD and PhD (Molecular and Cellular Biology) degree from Université Laval in 1996. He then completed his residency certification at the Université de Sherbrooke in 1998. He is currently associate professor of medicine at Université Laval and associate professor of biochemistry at Université de Moncton, University of NB and l'Université de Sherbrooke. He is a Board member of the New Brunswick Health Research Foundation, the New Brunswick Medical Society, the New Brunswick Innovation Foundation and the Beatrice Hunter Cancer Research Institute. Dr. Ouellette has also been active on many national bodies. 
 
 

In addition to being actively involved in cancer research initiatives and forging strategic partnerships Dr. Ouellette has published a number of scientific papers and articles.

 
 
 
 
Publications
 
Nicolas Crapoulet, Pierre O’Brien, Rodney Ouellette and Gilles A. Robichaud, Coordinated expression of Pax-5 and FAK1 in metastasis. In press, Anti-Cancer Agents in Medicinal Chemistry, June 2011
 
Narayansingh R, Ouellette RJ. Paired box gene 5 may modulate Proviral Integration of Moloney virus 2 gene and protein expression in mature B-cells. Leukemia and Lymphoma. 2011 May;52(5):887-95. Epub 2011 Feb 8.
 
David A. Barnett, and Rodney J. Ouellette "Elimination of the helium requirement in high-field asymmetric waveform ion mobility spectrometry (FAIMS): beneficial effects of decreasing the analyzer gap width on peptide analysis" Rapid Communications in Mass Sepctrometry, 2011, 25, 1-13 Accepted May 2 2011

Miroslava Cuperlovic-Culf, Nabil Belacel, Michelle Davey, and Rodney J. Ouellette "Multi-gene biomarkers panel for reference free prostate cancer diagnosis: determination and independent validation", Biomarkers, 2010, 1-13, (Received 04 June 2010; revised 16 July 2010; accepted 25 July 2010)

Adrian S. Culf and Rodney J. Ouellette "Solid-Phase Synthesis of N-Substituted Glycine Oligomers (α-Peptoids) and Derivatives" Molecules 2010, 15(8), 5282-5335; doi:10.3390/molecules15085282 Received: 4 June 2010; in revised form: 14 July 2010 / Accepted: 2 August 2010 / Published: 4 August 2010

Arseneau JR, Laflamme M, Lewis SM, Maïcas E, Ouellette RJ.(2009) Multiple isoforms of PAX5 are expressed in both lymphomas and normal B-cells.  Br J Haematol. 2009 Nov;147(3):328-38. Epub 2009 Sep 1.

M. Cuperlovic-Culf, N. Belacel, A.S. Culf, I.C. Chute, R.J. Ouellette, I.W. Burton, T.K. Karakach, J.A. Walter “NMR metabolic analysis of samples using fuzzy K-means clustering” Magn. Reson. Chem. 47, (2009) Accepted and In press.

 
        
Robichaud GA, Perreault JP, Ouellette RJ. Development of an isoform-specific gene suppression system: the study of the human Pax-5B transcriptional element. Nucleic Acids Res. 2008 Aug;36(14):4609-20. Epub 2008 Jul 10.
 
Culf, C A., Laflamme, M. Cuperlovic-Culf., M Ouellette, R.J.  Fast Deprotection of Synthetic Oligodeoxyribonucleotides using Standard Reagents under Microwave Irradiation. Oligonucleotides 2007 (Accepted)
 
Lucier, J.F., Bergeron, L.J., Brière, F.P., Ouellette R.J., Abou Elela, S and Perreault, J.P. RiboSubstrates: a web application addressing the cleavage specificities of ribozymes in designated genomes. BMC Bioinformatics 2006 7:480
 
Cuperlovic-Culf., M., Belacil, N., Culf, A., and Ouellette, R.J. Microarray Analysis of Alternative Splicing. Omics. 2006 10(3):344-57
 
Culf, A., Ouellette, R.J. and Cuperlovic-Culf., M. Carbohydrate Microarrays - Survey of Fabrication Techniques. Omics 2006 10(3):289-310
 
Cuperlovic-Culf, M., Culf, A.S., Laflamme, M., Ouellette, R.J., and Westcott S.A. Genomic analysis of the effects of boron compounds on a cell. Laboratory Focus 2006 10 (5), 8-9.
 
Cuperlovic-Culf., M., Belacil, N., Culf, A., and Ouellette, R.J. Data Analysis of Alternative Splicing Microarrays. Drug Discovery Today. 2006 11(21-22):983-90
 
Sonier, B., Arseneault, M., Lavigne,C., Ouellette, R.J., Vaillancourt, C. The 5-HT2A serotoninergic receptor is expressed in the MCF7 human breast cancer cell line and reveals a mitogenic effect of serotonin. Biochemical and Biophysical Research Communications. 2006 343(4):1053-9.
 
Lanoix, D., Ouellette R.J., and Vaillancourt, C. Expression of melatoninergic receptors in human placental choriocarcinoma cell lines. Human Reproduction. 2006 21(8):1981-9
 
Tao, T., Robichaud, A., Nadeau, S., Savoie, R., Gallant, B. and Ouellette, R.J. Optimisation of human oocytes for IVF and ICSI by hormonal stimulation and removal of cumulus cells. Journal of Assisted Reproduction and Genetics. 2006 23(1):23-8
 
Blacquiere, J.M., Sicora, O., Vogels, C.M., Cuperlovic-Culf, M. Decken, A., Ouellette, R.J. and Westcott, S.A. Dihydropyrimidinones containing boronic acids. Canadian Journal of Chemistry. Canadian Journal of Chemistry 83: 2052–2059 (2005)
 
Cuperlovic-Culf, M., Belacel, N., and Ouellette, R.J. Gene Selection in the Application of Microarrays in Tumour Diagnosis and Prognosis Drug Discovery Today. 10:429-37 (2005)
 
Sonier, B., Lavigne, C., Arseneault, M., Ouellette, R.J. and Vaillancourt, C. Expression of the 5-HT2A serotoninergic receptor in human placenta and choricocarcinoma cells: Mitogenic implications of serotonin. Placenta. 26:484-90. (2005)
 
Robichaud, G.A., Nardini, M., Laflamme, M. and Ouellette, R.J. Human Pax-5 C-terminal isoforms possess distinct transactivation properties and are differentially modulated in normal and malignant B cells. Journal of Biological Chemistry 279, 49956-49963 (2004)
 
Ouellette, R.J., Richard, D. and Maicas E. RT-PCR for Mammaglobin genes, MGB1 and MGB2, identifies breast cancer micrometastases in sentinel lymph nodes. American Journal of Clinical Pathology 121: 637-643 (2004)
 
Belacil, N., Cuperlovic-Culf., M., Laflamme, M., and Ouellette, R.J. Fuzzy J-means and VNS methods for clustering genes from microarray data. Bioinformatics 20: 1-20 (2004).
 
Belacil, N., Cuperlovic-Culf, M., Ouellette, R.J., and Boulassel, M.R. The Variable Neighborhood Search Metaheuristic for Fuzzy Clustering cDNA Microarray Gene Expression Data. IASTED Proceedings on Artificial Intelligence and Applications 51-57 (2004).
 
Tao, T., Robichaud, A.,Nadeau, S., Savoie, R., Gallant, B. and Ouellette, R.J. Effect of cumulus cell removal on the fertilization and the day 3 embryo quality in human IVF International Congress Series 1271, 135 - 138. (2004)
 
Cuperlovic-Culf, M., Robichaud, G.A., Nardini, M. and Ouellette, R.J. Theoretical functional analysis of Pax-5 isoforms. In Silico Biology 3: 453-469 (2003).
 
 
Posters

Adrian S. Culf, Rodney J. Ouellette Amine sub-monomers for α-peptoid synthesis”  7th Peptoid Summit at the "Molecular Foundry" of the "Lawrence Berkeley National Lab" in Berkeley, CA, USA, on August 9 - 10, 2010

A.S. Culf,M. Cuperlovic-Culf, R.J Ouellette Interesting 1H NMR Chemical Exchange Observed in Nitro SpiroBicyclic Zwitterionic Meisenheimer Complexes92nd Canadian Chemistry Conference and Exhibition. May 30 – June 3, 2009, Hamilton, ON. 

A.S. Culf,M. Cuperlovic-Culf, M. Laflamme, B.J. Tardiff, R.J. Ouellette, “Fast Deprotection of Synthetic Oligodeoxyribonucleotides using Standard Reagents under Microwave Irradiation” 92nd Canadian Chemistry Conference and Exhibition. May 30 – June 3, 2009, Hamilton, ON.

A.S. Culf, U. Werner-Zwanziger, K.N. Robertson, B.Chen, M. Cuperlovic-Culf, D.A. Barnett, R.J. Ouellette Polymeric and polymer-ligated SpiroBicyclic Zwitterionic Janovsky complexes” 92nd Canadian Chemistry Conference and Exhibition. May 30 – June 3, 2009, Hamilton, ON.

Adrian S. Culf, Jennifer A. Melanson, Daniel A. Léger, Rodney J. Ouellette Peptoid Preparation on the CEM Manual Peptide Synthesizer” at the "Molecular Foundry" of the "Lawrence Berkeley National Lab" in Berkeley, CA, USA, on August 9 - 10, 2010

 

 

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