DR. ADRIAN CULF, Ph.D.
Tel.: (506) 869-2020
Fax: (506) 862-7571
1994-1996 Postdoctoral Research Fellow (Isotope-assisted bio-organic synthesis & spectroscopy) – University of California, Santa Barbara with Prof. J. Tom Gerig.
1990-1994 Ph.D. (Isotope-assisted bio-organic synthesis & spectroscopy) – University of Surrey, Guildford (England), University of California, Berkeley and Lawrence Berkeley National Laboratory, with Prof. John. R. Jones (deceased), Dr. Phil G. Williams & Dr. William J.S. Lockley (Fisons Pharmaceuticals).
1986-1990 B.Sc. (Hons.) 1st. class honours (Chemistry) – University of Surrey, Guildford, England, including a one year research placement at British Petroleum Research, Sunbury-on-Thames, UK which was recognized with an Associateship of the University of Surrey, with distinction.
Adjunct professor, Chemistry, Mount Allison University, Sackville, NB.
Professeur associé, Chimie, Université de Moncton, Moncton, NB.
1. Synthesis of Bioactive Molecules.
a. Isoenzyme-selective HDAC inhibition.
b. 111In N,S-ligands for radio-diagnostic applications.
2. Study of protein-protein interactions with synthetic peptides and peptoids
Resin-based and membrane-based synthetic protocols and testing of anti-cancer biomacromolecular peptoids (N-Substituted glycine oligomers). Preparation of secondary structure libraries for cell culture screening.
3. Metabolomics by NMR spectroscopy.
a. Cell line experiments with cancer and normal cells.