Laboratory Services
Next Generation Sequencing (NGS)

The Atlantic Cancer Research Institute has partnered with the Molecular Genetics Laboratory to establish the Molecular Diagnostics and Sequencing Laboratory for clinical diagnostics in its Accreditation Canada approved and Ontario Laboratory Accreditation (OLA) laboratory located in the Dr. George-L.-Dumont University Hospital Centre (GLDUHC) in Moncton New-Brunswick.

Our aim is to provide accurate, timely and cost effective NGS diagnostic services to Physicians and other health professionals within the framework of an accredited clinical laboratory. This will ensure a better service within the province of New-Brunswick and elswhere by offering a more personalized approach to patient care.

The facility is supported by the Atlantic Cancer Research Institute (ACRI) and has opened two NGS systems by Life technologies Ion PGM™. ACRI also has two platforms on hand in their laboratories for research purposes.

The facility is open for diagnostics and we welcome discussions about how the laboratory can help support your needs. Please contact us for further information.


NGS diagnostic services

We currently have NGS services for various diseases, including cancer diagnostics. We also offer Exome sequencing for diagnostic of genetic diseases. 

If you wish to explore any further clinical developments, please contact us to discuss how we could help.

Poster Presentation
: Validation of two next-generation sequencing cancer panels for clinical testing 

Technical information for clinicians

Current available NGS services:

NGS Panel

Genes

Ion AmpliSeq™ Colon and Lung Cancer Panel

KRAS, EGFR, BRAF, PIK3CA, AKT1, ERBB2, PTEN, NRAS, STK11, MAP2K1, ALK, DDR2, CTNNB1, MET, TP53, SMAD4, FBXW7, FGFR3, NOTCH1, ERBB4, FGFR1, FGFR2


Ion AmpliSeq™ Cancer Hotspot Panel v2



ABL1, AKT1, ALK, APC, ATM, BRAF, CDH1, CDKN2A, CSF1R, CTNNB1, EGFR, ERBB2, ERBB4, EZH2, FBXW7, FGFR1, FGFR2, FGFR3, FLT3, GNA11, GNAQ, GNAS, HNF1A, HRAS, IDH1, IDH2, JAK2, JAK3, KDR, KIT, KRAS, MET, MLH1, MPL, NOTCH1, NPM1, NRAS, PDGFRA, PIK3CA, PTEN, PTPN11, RB1, RET, SMAD4, SMARCB1, SMO, SRC, STK11, TP53 and VHL

Ion AmpliSeqExome Panel



This test analyzes the exons of about 93-97% of all medically relevant genes at the same time and compares it to those of healthy people to identify DNA changes that are related to the individual's medical condition. 

Ion AmpliSeq™ BRCA1 and BRCA2 Panel

BRCA1, BRCA2

**In validation process





Ion AmpliSeq™ Inherited Disease Panel

*Full list of Genes HERE






Neuromuscular        245 Diseases
                               87 Genes

Heart disease          159 Diseases
                               62 Genes

Developmental        193 Diseases
                               75 Genes

Metabolic                  46 Diseases
                               28 Genes

Other                     210 Diseases
          73 Genes
(Inherited cancer, blindness
, etc.)

**In validation process 

**Please note that all requisition forms must be submitted by a licensed Physician, Genetics Counselor or Pathologist.
 



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Atlantic Cancer Research Institute 
Pavillon Hôtel-Dieu
35, Providence Street
Moncton, NB E1C 8X3 Canada

info@canceratl.ca
Tel.: 506-862-7512
Fax.: 506-862-7571

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The Atlantic Cancer Research Institute

 (ACRI) is a non-profit organization founded in late 1998 and housed at the Dr. Georges-L.-Dumont University Hospital Centre in Moncton. Thanks to its unique expertise, ACRI has become a true centre of excellence in cancer research.

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